Metabolic insights from a GHSR-A203E mutant mouse model

Metabolic insights from a GHSR-A203E mutant mouse model

Objective: Binding of ghrelin to its receptor, growth hormone secretagogue receptor (GHSR), stimulates GH release, induces eating, and increases blood glucose. These processes may also be influenced by constitutive (ghrelin-independent) GHSR activity, as suggested by findings in short people with na...

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Bibliographic Details
Main Authors: Lola J. Torz, Sherri Osborne-Lawrence, Juan Rodriguez, Zhenyan He, María Paula Cornejo, Emilio Román Mustafá, Chunyu Jin, Natalia Petersen, Morten A. Hedegaard, Maja Nybo, Valentina Martínez Damonte, Nathan P. Metzger, Bharath K. Mani, Kevin W. Williams, Jesica Raingo, Mario Perello, Birgitte Holst, Jeffrey M. Zigman
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Metabolism
Subjects:
Ghrelin
Constitutive activity
Growth hormone
GH
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820300788

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http://www.sciencedirect.com/science/article/pii/S2212877820300788

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