Aromatic amino acid activation of signaling pathways in bone marrow mesenchymal stem cells depends on oxygen tension.

Aromatic amino acid activation of signaling pathways in bone marrow mesenchymal stem cells depends on oxygen tension.

The physiologic oxygen pressures inside the bone marrow environment are much lower than what is present in the peripheral circulation, ranging from 1-7%, compared to values as high as 10-13% in the arteries, lungs and liver. Thus, experiments done with bone marrow mesenchymal stem cells (BMMSCs) usi...

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Bibliographic Details
Main Authors: Mona El Refaey, Qing Zhong, William D Hill, Xing-Ming Shi, Mark W Hamrick, Lakiea Bailey, Maribeth Johnson, Jianrui Xu, Wendy B Bollag, Norman Chutkan, Carlos M Isales
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3984069?pdf=render

Internet

http://europepmc.org/articles/PMC3984069?pdf=render

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