Forced expression of miR-143 represses ERK5/c-Myc and p68/p72 signaling in concert with miR-145 in gut tumors of Apc(Min) mice.

Forced expression of miR-143 represses ERK5/c-Myc and p68/p72 signaling in concert with miR-145 in gut tumors of Apc(Min) mice.

Recently, miR-143 and miR-145 have been shown to belong to a subset of microRNAs whose expression is controlled by a complex of a tumor suppressor p53 and DEAD-box RNA helicase subunits p68/p72. While accumulating studies have acknowledged that both miRNAs function as tumor suppressors and are simil...

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Bibliographic Details
Main Authors: Yuji Takaoka, Yuko Shimizu, Hitoki Hasegawa, Yasuo Ouchi, Shanlou Qiao, Miki Nagahara, Masatoshi Ichihara, Jiing-Dwan Lee, Koichi Adachi, Michinari Hamaguchi, Takashi Iwamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3410903?pdf=render

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http://europepmc.org/articles/PMC3410903?pdf=render

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