Aspergillus Fumigatus ZnfA, a Novel Zinc Finger Transcription Factor Involved in Calcium Metabolism and Caspofungin Tolerance

Aspergillus Fumigatus ZnfA, a Novel Zinc Finger Transcription Factor Involved in Calcium Metabolism and Caspofungin Tolerance

Invasive pulmonary aspergillosis is a life-threatening fungal infection especially in the immunocompromised patients. The low diversity of available antifungal drugs coupled with the emergence of antifungal resistance has become a worldwide clinical concern. The echinocandin Caspofungin (CSP) is rec...

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Main Authors: Clara Valero, Ana Cristina Colabardini, Patrícia Alves de Castro, Lilian Pereira Silva, Laure Nicolas Annick Ries, Lakhansing Pardeshi, Fang Wang, Marina Campos Rocha, Iran Malavazi, Roberto Nascimento Silva, Celso Martins, Patrícia Domingos, Cristina Pereira-Silva, Michael J. Bromley, Koon Ho Wong, Gustavo H. Goldman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Fungal Biology
Subjects:
Aspergillus fumigatus
caspofungin
calcium
transcription factors
cell wall
Online Access:https://www.frontiersin.org/articles/10.3389/ffunb.2021.689900/full

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https://www.frontiersin.org/articles/10.3389/ffunb.2021.689900/full

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