CCR5-Mediated Signaling Is Involved in Invasion of Glioblastoma Cells in Its Microenvironment

CCR5-Mediated Signaling Is Involved in Invasion of Glioblastoma Cells in Its Microenvironment

The chemokine CCL5/RANTES is a versatile inflammatory mediator, which interacts with the receptor CCR5, promoting cancer cell interactions within the tumor microenvironment. Glioblastoma is a highly invasive tumor, in which CCL5 expression correlates with shorter patient survival. Using immunohistoc...

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Bibliographic Details
Main Authors: Metka Novak, Miha Koprivnikar Krajnc, Barbara Hrastar, Barbara Breznik, Bernarda Majc, Mateja Mlinar, Ana Rotter, Andrej Porčnik, Jernej Mlakar, Katja Stare, Richard G. Pestell, Tamara Lah Turnšek
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
CCL5
CCR5
chemokines
glioblastoma
invasion
maraviroc
Online Access:https://www.mdpi.com/1422-0067/21/12/4199

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https://www.mdpi.com/1422-0067/21/12/4199

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