Hepatic stellate cells secrete Ccl5 to induce hepatocyte steatosis

Abstract Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of disease severity, starting from pure steatosis, leading to fatty inflammation labeled as non-alcoholic steatohepatitis (NASH), and finally fibrosis leading to cirrhosis. Activated hepatic stellate cells (HSCs) are know...

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Bibliographic Details
Main Authors: Byeong-Moo Kim, Ahmed Maher Abdelfattah, Robin Vasan, Bryan C. Fuchs, Michael Y. Choi
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25699-9