Synthesis of Triptorelin Lactate Catalyzed by Lipase in Organic Media

Synthesis of Triptorelin Lactate Catalyzed by Lipase in Organic Media

Triptorelin lactate was successfully synthesized by porcine pancreatic lipase (PPL)<em> </em>in organic solvents. The effects of acyl donor, substrate ratio, organic solvent, temperature, and water activity were investigated. Under the optimum conditions, a yield of 30% f...

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Bibliographic Details
Main Authors: Hong Zhuang, Zhi Wang, Jiaxin Wang, Hong Zhang, Erna Xun, Ge Chen, Hong Yue, Ning Tang, Lei Wang
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:International Journal of Molecular Sciences
Subjects:
triptorelin lactate
lipase
enzyme activity
esterification
Online Access:http://www.mdpi.com/1422-0067/13/8/9971

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http://www.mdpi.com/1422-0067/13/8/9971

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