Investigation of CBS, MTR, RFC-1 and TC Polymorphisms as Maternal Risk Factors for Down Syndrome

Recent evidence shows that almost 92% of the DS children are born from young mothers, suggesting that other risk factors than advanced maternal age must be involved. In this context, some studies demonstrated a possible link between DS and maternal polymorphisms in genes involved in folate metabolis...

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Bibliographic Details
Main Authors: N. Fintelman-Rodrigues, J. C. Corrêa, J. M. Santos, M. M. G. Pimentel, C. B. Santos-Rebouças
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2009-0626