Nicastrin-Like, a Novel Transmembrane Protein from <i>Trypanosoma cruzi</i> Associated to the Flagellar Pocket

Nicastrin-Like, a Novel Transmembrane Protein from <i>Trypanosoma cruzi</i> Associated to the Flagellar Pocket

Nicastrin (NICT) is a transmembrane protein physically associated with the polytypical aspartyl protease presenilin that plays a vital role in the correct localization and stabilization of presenilin to the membrane-bound γ-secretase complex. This complex is involved in the regulation of a wide rang...

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Bibliographic Details
Main Authors: Guilherme Curty Lechuga, Paloma Napoleão-Pêgo, Larissa Rodrigues Gomes, Andressa da Matta Durans, David William Provance, Salvatore Giovanni De-Simone
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Microorganisms
Subjects:
<i>Trypanosoma cruzi</i>
nicastrin
presenilin
γ-secretase
transmembrane motif
B-cell epitope
Online Access:https://www.mdpi.com/2076-2607/9/8/1750

Internet

https://www.mdpi.com/2076-2607/9/8/1750

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