Adjuvant melatonin for the prevention of recurrence and mortality following lung cancer resection (AMPLCaRe): A randomized placebo controlled clinical trial

Background: Despite curative intent resection in patients with non-small cell lung cancer (NSCLC), recurrence leading to mortality remains too common. Melatonin has shown promise for the treatment of patients with lung cancer; however, its effect following cancer resection has not been studied. We e...

Full description

Bibliographic Details
Main Authors: Dugald Seely, Mark Legacy, Rebecca C. Auer, Anna Fazekas, Edita Delic, Caitlin Anstee, Leonard Angka, Michael A. Kennedy, Lee-Hwa Tai, Tinghua Zhang, Donna E. Maziak, Farid M. Shamji, R. Sudhir Sundaresan, Sebastien Gilbert, P. James Villeneuve, Ahmad S. Ashrafi, Richard Inculet, Kazuhiro Yasufuku, Thomas K. Waddell, Christian Finley, Yaron Shargall, Madelaine Plourde, Dean A. Fergusson, Tim Ramsay, Andrew J.E. Seely
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:EClinicalMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537021000432