Comparison of the Mismatch Repair System between Primary and Metastatic Colorectal Cancers Using Immunohistochemistry

Comparison of the Mismatch Repair System between Primary and Metastatic Colorectal Cancers Using Immunohistochemistry

Background Colorectal cancer (CRC) is one of the most common malignancies worldwide. Approximately 10%–15% of the CRC cases have defective DNA mismatch repair (MMR) genes. Although the high level of microsatellite instability status is a predictor of favorable outcome in primary CRC, little is known...

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Bibliographic Details
Main Authors: Jiyoon Jung, Youngjin Kang, Yoo Jin Lee, Eojin Kim, Bokyung Ahn, Eunjung Lee, Joo Young Kim, Jeong Hyeon Lee, Youngseok Lee, Chul Hwan Kim, Yang-Seok Chae
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2017-03-01
Series:Journal of Pathology and Translational Medicine
Subjects:
Colorectal neoplasms
DNA mismatch repair
Microsatellite instability
Immunohistochemistry
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2016-12-09.pdf

Internet

http://www.jpatholtm.org/upload/pdf/jptm-2016-12-09.pdf

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