Recombinant Botulinum Neurotoxin Hc Subunit (BoNT Hc) and Catalytically Inactive Clostridium botulinum Holoproteins (ciBoNT HPs) as Vaccine Candidates for the Prevention of Botulism

Recombinant Botulinum Neurotoxin Hc Subunit (BoNT Hc) and Catalytically Inactive Clostridium botulinum Holoproteins (ciBoNT HPs) as Vaccine Candidates for the Prevention of Botulism

There are few available medical countermeasures against botulism and the discontinuation of the pentavalent botulinum toxoid vaccine by the Centers for Disease Control and Prevention in 2011 has resulted in the need for a safe and effective prophylactic alternative. Advances in genetic engineering h...

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Bibliographic Details
Main Authors: Robert P. Webb, Theresa J. Smith, Leonard A. Smith, Patrick M. Wright, Rebecca L. Guernieri, Jennifer L. Brown, Janet C. Skerry
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Toxins
Subjects:
Clostridium botulinum
botulinum neurotoxin (BoNT)
vaccine
catalytically inactive BoNT holoprotein (ciBoNT HP)
BoNT subtype toxin
BoNT mosaic toxin.
Online Access:https://www.mdpi.com/2072-6651/9/9/269

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https://www.mdpi.com/2072-6651/9/9/269

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