Combined Effects of PPARγ Agonists and Epidermal Growth Factor Receptor Inhibitors in Human Proximal Tubule Cells

We aimed to determine whether epidermal growth factor receptor (EGFR) inhibition, in addition to a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, prevents high-glucose-induced proximal tubular fibrosis, inflammation, and sodium and water retention in human proximal tubule cells ex...

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Bibliographic Details
Main Authors: Katherine Pegg, Jie Zhang, Carol Pollock, Sonia Saad
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2013/982462