Random walks on mutual microRNA-target gene interaction network improve the prediction of disease-associated microRNAs

Abstract Background MicroRNAs (miRNAs) have been shown to play an important role in pathological initiation, progression and maintenance. Because identification in the laboratory of disease-related miRNAs is not straightforward, numerous network-based methods have been developed to predict novel miR...

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Bibliographic Details
Main Authors: Duc-Hau Le, Lieven Verbeke, Le Hoang Son, Dinh-Toi Chu, Van-Huy Pham
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-017-1924-1