Selection of target sites for mobile DNA integration in the human genome.

DNA sequences from retroviruses, retrotransposons, DNA transposons, and parvoviruses can all become integrated into the human genome. Accumulation of such sequences accounts for at least 40% of our genome today. These integrating elements are also of interest as gene-delivery vectors for human gene...

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Bibliographic Details
Main Authors: Charles Berry, Sridhar Hannenhalli, Jeremy Leipzig, Frederic D Bushman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0020157