Intrathymic differentiation of natural antibody-producing plasma cells in human neonates

Intrathymic differentiation of natural antibody-producing plasma cells in human neonates

The thymus is known as the organ of T lymphocyte development. Here authors show that terminal B cell differentiation also takes place in the thymus of human neonates, leading to antibody production against commensal and pathogenic bacteria.

Bibliographic Details
Main Authors: Hector Cordero, Rodney G. King, Pranay Dogra, Chloe Dufeu, Sarah B. See, Alexander M. Chong, Anne-Catrin Uhlemann, Siu-Hong Ho, David M. Kalfa, Emile A. Bacha, John F. Kearney, Emmanuel Zorn
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-26069-2

Internet

https://doi.org/10.1038/s41467-021-26069-2

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