Amplification of the Insulin-Like Growth Factor 1 Receptor Gene Is a Rare Event in Adrenocortical Adenocarcinomas: Searching for Potential Mechanisms of Overexpression

Amplification of the Insulin-Like Growth Factor 1 Receptor Gene Is a Rare Event in Adrenocortical Adenocarcinomas: Searching for Potential Mechanisms of Overexpression

Context. IGF1R overexpression appears to be a prognostic biomarker of metastatic pediatric adrenocortical tumors. However, the molecular mechanisms that are implicated in its upregulation remain unknown. Aim. To investigate the potential mechanisms involved in IGF1R overexpression. Patients and Meth...

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Bibliographic Details
Main Authors: Tamaya Castro Ribeiro, Alexander Augusto Jorge, Madson Q. Almeida, Beatriz Marinho de Paula Mariani, Mirian Yumi Nishi, Berenice Bilharinho Mendonca, Maria Candida Barisson Villares Fragoso, Ana Claudia Latronico
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/936031

Internet

http://dx.doi.org/10.1155/2014/936031

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