Induction of autoantibodies against lung matrix proteins and smoke-induced inflammation in mice

<p>Abstract</p> <p>Background</p> <p>Smoking is the major etiologic factor in COPD, yet the exact underlying pathogenetic mechanisms have not been elucidated. Since a few years, there is mounting evidence that a specific immune response, partly present as an autoimmune...

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Bibliographic Details
Main Authors: Hylkema Machteld N, Postma Dirkje S, Jekel Henrike, Geerlings Marie, Timens Wim, Brandsma Corry-Anke, Kerstjens Huib AM
Format: Article
Language:English
Published: BMC 2010-12-01
Series:BMC Pulmonary Medicine
Online Access:http://www.biomedcentral.com/1471-2466/10/64