Doxorubicin-loaded pH-sensitive micelles: A promising alternative to enhance antitumor activity and reduce toxicity

Doxorubicin-loaded pH-sensitive micelles: A promising alternative to enhance antitumor activity and reduce toxicity

Doxorubicin (DOX) is an anthracycline antibiotic widely used in the treatment of cancer, however, it is associated with the occurrence of adverse reactions that limits its clinical use. In this context, the encapsulation of DOX in micelles responsive to pH variations has shown to be a strategy for t...

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Bibliographic Details
Main Authors: Carolina Henriques Cavalcante, Renata Salgado Fernandes, Juliana de Oliveira Silva, Caroline Mari Ramos Oda, Elaine Amaral Leite, Geovanni Dantas Cassali, Ives Charlie-Silva, Bianca Helena Ventura Fernandes, Lucas Antônio Miranda Ferreira, Andre Luis Branco de Barros
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Micelles
pH-sensitivity
Doxorubicin
Antitumor
Drug delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220312695

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http://www.sciencedirect.com/science/article/pii/S0753332220312695

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