Known allergen structures predict Schistosoma mansoni IgE binding antigens in human infection

Known allergen structures predict Schistosoma mansoni IgE binding antigens in human infection

The IgE response has been associated with both allergic reactions and immunity to metazoan parasites. Recently we hypothesized that all environmental allergens bear structural homology to IgE binding antigens from metazoan parasites and that this homology defines the relatively small number of prote...

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Bibliographic Details
Main Authors: Edward John Farnell, Nidhi eTyagi, Stephanie eRyan, Iain eChalmers, Angela ePinot de Moria, Jakub eWawrzyniak, Frances eJones, Colin Matthew Fitzsimmons, Edridah Muheki Tukahebwa, Nicholas eFurnham, Rick eMaizels, David eDunne
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Immunology
Subjects:
Helminth Proteins
Schistosomiasis mansoni
IgE
IgG4
Allergenicity
parasite allergens
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00026/full

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http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00026/full

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