Influence of probiotic bacteria on gut microbiota composition and gut wall function in an in-vitro model in patients with Parkinson's disease

Influence of probiotic bacteria on gut microbiota composition and gut wall function in an in-vitro model in patients with Parkinson's disease

We report here the potential role of a 4-strain probiotic suspension for use with patients with Parkinson's disease (PD). Stool samples from a group of three patients with diagnosed PD were used to create microbiotas in an in-vitro gut model. The effects of dosing with an oral probiotic suspens...

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Bibliographic Details
Main Authors: Jonas Ghyselinck, Lynn Verstrepen, Frédéric Moens, Pieter Van Den Abbeele, Arnout Bruggeman, Jawal Said, Barry Smith, Lynne Ann Barker, Caroline Jordan, Valentina Leta, K. Ray Chaudhuri, Abdul W. Basit, Simon Gaisford
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Probiotics
Gastrointestinal microbiome
Lactobacillus
Parkinson's disease
Epithelial gut wall integrity
Butyrate
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156721000165

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http://www.sciencedirect.com/science/article/pii/S2590156721000165

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