TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer

TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer

Transforming growth factor-β (TGF-β) is a cytokine essential for the induction of the fibrotic response and for the activation of the cancer stroma. Strong evidence suggests that a strong cross-talk exists among TGF-β and the tissue extracellular matrix components. TGF-&am...

Full description

Bibliographic Details
Main Authors: Laia Caja, Francesco Dituri, Serena Mancarella, Daniel Caballero-Diaz, Aristidis Moustakas, Gianluigi Giannelli, Isabel Fabregat
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Molecular Sciences
Subjects:
TGF-β
fibrosis
cancer
HCC
microenvironment
CAF
hepatic stellate cells
extracellular matrix
galunisertib
Online Access:http://www.mdpi.com/1422-0067/19/5/1294

Internet

http://www.mdpi.com/1422-0067/19/5/1294

Similar Items