Molecular Dynamics Simulations Reveal Canonical Conformations in Different pMHC/TCR Interactions

Molecular Dynamics Simulations Reveal Canonical Conformations in Different pMHC/TCR Interactions

The major defense system against microbial pathogens in vertebrates is the adaptive immune response and represents an effective mechanism in cancer surveillance. T cells represent an essential component of this complex system. They can recognize myriads of antigens as short peptides (p) originated f...

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Bibliographic Details
Main Authors: Josephine Alba, Lorenzo Di Rienzo, Edoardo Milanetti, Oreste Acuto, Marco D’Abramo
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
molecular dynamics
biophysics
protein-membrane
T cell antigen receptor.
Online Access:https://www.mdpi.com/2073-4409/9/4/942

Internet

https://www.mdpi.com/2073-4409/9/4/942

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