17β-Estradiol reduces tumor necrosis factor-α-mediated LDL accumulation in the artery wall
Estrogens have direct effects on the vascular wall that may prevent the development of atherosclerosis. In particular, estrogens, such as 17β-estradiol (estradiol), are known to have potent antioxidant activity. Tumor necrosis factor-α (TNF) is found in human atheroma and produces oxygen-derived fre...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1999-03-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520324421 |