Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution
Imaging mass spectrometry is a powerful emerging tool for mapping the spatial distribution of biomolecules across tissue surfaces. Here the authors showcase an automated technology for deep proteome imaging that utilizes ultrasensitive microfluidics and a mass spectrometry workflow to analyze tissue...
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Bibliographic Details
| Main Authors: |
Paul D. Piehowski,
Ying Zhu,
Lisa M. Bramer,
Kelly G. Stratton,
Rui Zhao,
Daniel J. Orton,
Ronald J. Moore,
Jia Yuan,
Hugh D. Mitchell,
Yuqian Gao,
Bobbie-Jo M. Webb-Robertson,
Sudhansu K. Dey,
Ryan T. Kelly,
Kristin E. Burnum-Johnson |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2020-01-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-13858-z
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