CLCA2 is a positive regulator of store-operated calcium entry and TMEM16A.

The Chloride Channel Accessory (CLCA) protein family was first characterized as regulators of calcium-activated chloride channel (CaCC) currents (ICaCC), but the mechanism has not been fully established. We hypothesized that CLCAs might regulate ICaCC by modulating intracellular calcium levels. In c...

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Bibliographic Details
Main Authors: Aarushi Sharma, Grace Ramena, Yufang Yin, Louis Premkumar, Randolph C Elble
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5951673?pdf=render