N-glycoproteome analysis of the secretome of human metastatic hepatocellular carcinoma cell lines combining hydrazide chemistry, HILIC enrichment and mass spectrometry.

Cancer cell metastasis is a major cause of cancer death. Unfortunately, the underlying molecular mechanisms remain unknown, which results in the lack of efficient diagnosis, therapy and prevention approaches. Nevertheless, the dysregulation of the cancer cell secretome is known to play key roles in...

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Bibliographic Details
Main Authors: Xianyu Li, Jing Jiang, Xinyuan Zhao, Jifeng Wang, Huanhuan Han, Yan Zhao, Bo Peng, Rugang Zhong, Wantao Ying, Xiaohong Qian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3852754?pdf=render