A majority of Brazilian patients with rheumatoid arthritis HLA-DRB1 alleles carry both the HLA-DRB1 shared epitope and anti-citrunillated peptide antibodies

A majority of Brazilian patients with rheumatoid arthritis HLA-DRB1 alleles carry both the HLA-DRB1 shared epitope and anti-citrunillated peptide antibodies

The objective of the present study was to evaluate the contribution of the shared epitope (SE), the rheumatoid arthritis (RA) protection model, and the occurrence of anti-cyclic citrullinated peptide (anti-CCP) antibodies in RA patients from a genetically diverse population. One hundred and forty Br...

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Bibliographic Details
Main Authors: P. Louzada-Júnior, M.V.C. Freitas, R.D.R. Oliveira, N.H.S. Deghaide, R.A. Conde, M.B. Bertolo, E.A. Donadi
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2008-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Susceptibility to rheumatoid arthritis
HLA
Brazilians
Shared epitope
Anti-cyclic citrullinated peptide
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000600010

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000600010

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