Evaluation of the concentration of malondialdehyde and nitrite in patients with sickle cell anemia treated or not with hydroxyurea

Evaluation of the concentration of malondialdehyde and nitrite in patients with sickle cell anemia treated or not with hydroxyurea

Objective: To determine the serum levels of malondialdehyde and nitrite in patients with sickle cell anemia treated or not with hydroxyurea in outpatient’s setting. Methods: Of the 65 patients with sickle cell anemia selected for the study, 51 were not treated with hydroxyurea (Group 1), 14 made chr...

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Bibliographic Details
Main Authors: Darcielle Bruna Dias Elias, Rivelilson Mendes de Freitas, Romélia Pinheiro Gonçalves, Hemerson Yuri Ferreira Magalhães, Jacqueline Holanda de Sousa, Silvia Maria Meira Magalhães
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2010-12-01
Series:Einstein (São Paulo)
Subjects:
Anemia
sickle cell/drug therapy
Malondialdehyde
Thiobarbituric acid reactive substances
Nitrite
Oxidative stress
Hydroxyurea/therapeutic use
Online Access:http://apps.einstein.br/revista/arquivos/PDF/1731-Einsteinv8n4_pg414-418_eng.pdf

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http://apps.einstein.br/revista/arquivos/PDF/1731-Einsteinv8n4_pg414-418_eng.pdf

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