Glypicans define unique roles for the Hedgehog co-receptors boi and ihog in cytoneme-mediated gradient formation

Glypicans define unique roles for the Hedgehog co-receptors boi and ihog in cytoneme-mediated gradient formation

The conserved family of Hedgehog (Hh) signaling proteins plays a key role in cell–cell communication in development, tissue repair, and cancer progression, inducing distinct concentration-dependent responses in target cells located at short and long distances. One simple mechanism for long distance...

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Bibliographic Details
Main Authors: Eléanor Simon, Carlos Jiménez-Jiménez, Irene Seijo-Barandiarán, Gustavo Aguilar, David Sánchez-Hernández, Adrián Aguirre-Tamaral, Laura González-Méndez, Pedro Ripoll, Isabel Guerrero
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
hedgehog signaling
ihog
boi
glypicans
cytonemes
Online Access:https://elifesciences.org/articles/64581

Internet

https://elifesciences.org/articles/64581

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