Immunogenic Cell Death Inducing Fluorinated Mitochondria‐Disrupting Helical Polypeptide Synergizes with PD‐L1 Immune Checkpoint Blockade

Immunogenic Cell Death Inducing Fluorinated Mitochondria‐Disrupting Helical Polypeptide Synergizes with PD‐L1 Immune Checkpoint Blockade

Abstract Immunogenic cell death (ICD) is distinguished by the release of tumor‐associated antigens (TAAs) and danger‐associated molecular patterns (DAMPs). This cell death has been studied in the field of cancer immunotherapy due to the ability of ICD to induce antitumor immunity. Herein, endoplasmi...

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Bibliographic Details
Main Authors: Seong Dong Jeong, Bo‐Kyeong Jung, Hyo Min Ahn, DaeYong Lee, JongHoon Ha, Ilkoo Noh, Chae‐Ok Yun, Yeu‐Chun Kim
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Advanced Science
Subjects:
combination cancer immunotherapy
immune checkpoint blockade
immunogenic cell death
mitochondrial membrane destabilization
α‐helical polypeptide
Online Access:https://doi.org/10.1002/advs.202001308

Internet

https://doi.org/10.1002/advs.202001308

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