Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach

Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach

Heat shock protein (Hsp) synthesis is upregulated in a wide range of cancers to provide the appropriate environment for tumor progression. The Hsp110 and Hsp70 families have been associated to cancer cell survival and resistance to chemotherapy. In this study, we explore the strategy of drug repurpo...

Full description

Bibliographic Details
Main Authors: Leire Dublang, Jarl Underhaug, Marte I. Flydal, Lorea Velasco-Carneros, Jean-Didier Maréchal, Fernando Moro, Maria Dolores Boyano, Aurora Martinez, Arturo Muga
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
chaperones
drug repurposing
inhibitors
melanoma
pinaverium bromide
Online Access:https://www.mdpi.com/2072-6694/13/12/2936

Internet

https://www.mdpi.com/2072-6694/13/12/2936

Similar Items