Complement Component 3 Negatively Regulates Antibody Response by Modulation of Red Blood Cell Antigen

Complement Component 3 Negatively Regulates Antibody Response by Modulation of Red Blood Cell Antigen

Red blood cell (RBC) alloimmunization can make it difficult to procure compatible RBCs for future transfusion, directly leading to increased morbidity and mortality in transfusion-dependent patients. However, the factors that regulate RBC alloimmunization remain incompletely understood. As complemen...

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Bibliographic Details
Main Authors: Amanda Mener, Connie M. Arthur, Seema R. Patel, Jingchun Liu, Jeanne E. Hendrickson, Sean R. Stowell
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
red blood cells
complement component 3
alloimmunization
antigen modulation
humoral immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.00676/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.00676/full

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