Clinical pharmacogenomic testing of <it>KRAS, BRAF </it>and <it>EGFR </it>mutations by high resolution melting analysis and ultra-deep pyrosequencing

<p>Abstract</p> <p>Background</p> <p>Epidermal growth factor receptor (<it>EGFR</it>) and its downstream factors <it>KRAS </it>and <it>BRAF </it>are mutated in several types of cancer, affecting the clinical response to EGFR inhibitor...

Full description

Bibliographic Details
Main Authors: Agúndez José AG, Arcusa Àngels, Mañé Begoña, Martí Isabel, Dias Miguel, Gamundi María, Hernan Imma, Jurado Ismael, Borràs Emma, Blanca Miguel, Carballo Miguel
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/406