Improved Resolution of 4-Chloromandelic Acid and the Effect of Chlorine Interactions Using (<i>R</i>)-(+)-Benzyl-1-Phenylethylamine as a Resolving Agent

Improved Resolution of 4-Chloromandelic Acid and the Effect of Chlorine Interactions Using (<i>R</i>)-(+)-Benzyl-1-Phenylethylamine as a Resolving Agent

In order to avoid the disadvantage of commonly used resolving agent 1-phenylethylamine (hereafter: PEA), which is soluble in water, (<i>R</i>)-(+)-benzyl-1-phenylethylamine ((<i>R</i>)-(+)-BPA) was used to resolve 4-chloromandelic acid (4-ClMA) in this study. The optimal reso...

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Bibliographic Details
Main Authors: Yangfeng Peng, Cai Feng, Sohrab Rohani, Quan He
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
chlorine interactions
4-chloromandelic acid
benzyl-1-phenylethylamine
chiral discrimination
resolution
Online Access:https://www.mdpi.com/1420-3049/23/12/3354

Internet

https://www.mdpi.com/1420-3049/23/12/3354

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