Synthesis and testing of the first azobenzene mannobioside as photoswitchable ligand for the bacterial lectin FimH

In order to allow spatial and temporal control of carbohydrate-specific bacterial adhesion, it has become our goal to synthesise azobenzene mannosides as photoswitchable inhibitors of type 1 fimbriae-mediated adhesion of E. coli. An azobenzene mannobioside 2 was prepared and its photochromic propert...

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Bibliographic Details
Main Authors: Vijayanand Chandrasekaran, Katharina Kolbe, Femke Beiroth, Thisbe K. Lindhorst
Format: Article
Language:English
Published: Beilstein-Institut 2013-02-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.9.26