Dilution of oral D3‐Creatine to measure creatine pool size and estimate skeletal muscle mass: development of a correction algorithm

Dilution of oral D3‐Creatine to measure creatine pool size and estimate skeletal muscle mass: development of a correction algorithm

Abstract Background Muscle mass can be measured directly in vivo by isotope dilution, using Creatine‐(methyl‐d3) monohydrate (D3‐Cr) by mouth followed by measurement of the steady‐state enrichment of D3‐creatinine (D3‐Crn) in urine. Isotope dilution methods require knowledge of the amount of tracer...

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Bibliographic Details
Main Authors: Mahalakshmi Shankaran, Gregg Czerwieniec, Chancy Fessler, Po‐yin Anne Wong, Salena Killion, Scott M. Turner, Marc K. Hellerstein, William J. Evans
Format: Article
Language:English
Published: Wiley 2018-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Muscle mass
Creatine
Creatinine
Urine
Body composition
Online Access:https://doi.org/10.1002/jcsm.12278

Internet

https://doi.org/10.1002/jcsm.12278

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