Exploring IDP–Ligand Interactions: tau K18 as A Test Case

Over the past decade intrinsically disordered proteins (IDPs) have emerged as a biologically important class of proteins, many of which are of therapeutic relevance. Here, we investigated the interactions between a model IDP system, tau K18, and nine literature compounds that have been reported as h...

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Bibliographic Details
Main Authors: Darius Vagrys, James Davidson, Ijen Chen, Roderick E. Hubbard, Ben Davis
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/15/5257