Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats.

Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats.

<h4>Background</h4>In this study, the neuroprotective effect of a novel nonpeptide AT2R agonist, C21, was examined in a conscious model of stroke to verify a class effect of AT2R agonists as neuroprotective agents.<h4>Methods and results</h4>Spontaneously hypertensive rats (S...

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Bibliographic Details
Main Authors: Claudia A McCarthy, Antony Vinh, Alyson A Miller, Anders Hallberg, Mathias Alterman, Jennifer K Callaway, Robert E Widdop
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24752645/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24752645/?tool=EBI

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