Characterization of Epileptic Spiking Associated With Brain Amyloidosis in APP/PS1 Mice

Characterization of Epileptic Spiking Associated With Brain Amyloidosis in APP/PS1 Mice

Epileptic activity without visible convulsions is common in Alzheimer's disease (AD) and may contribute adversely to the disease progress and symptoms. Transgenic mice with amyloid plaque pathology also display epileptic seizures, but those are too infrequent to assess the effect of anti-epilep...

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Bibliographic Details
Main Authors: Irina Gureviciene, Irina Ishchenko, Sofya Ziyatdinova, Nanxiang Jin, Arto Lipponen, Kestutis Gurevicius, Heikki Tanila
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neurology
Subjects:
Alzheimer's disease
amyloid - beta- protein
transgenic
EEG
sleep
epilepsy
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01151/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.01151/full

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