Characterization of Epileptic Spiking Associated With Brain Amyloidosis in APP/PS1 Mice
Epileptic activity without visible convulsions is common in Alzheimer's disease (AD) and may contribute adversely to the disease progress and symptoms. Transgenic mice with amyloid plaque pathology also display epileptic seizures, but those are too infrequent to assess the effect of anti-epilep...
Main Authors: | Irina Gureviciene, Irina Ishchenko, Sofya Ziyatdinova, Nanxiang Jin, Arto Lipponen, Kestutis Gurevicius, Heikki Tanila |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-11-01
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Series: | Frontiers in Neurology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2019.01151/full |
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