Optimization of a HPLC procedure for simultaneous determination of cisplatin and the complex cis,cis,trans-diamminedichlorodihydroxoplatinum(IV) in aqueous solutions

Optimization of a HPLC procedure for simultaneous determination of cisplatin and the complex cis,cis,trans-diamminedichlorodihydroxoplatinum(IV) in aqueous solutions

A RP-HPLC procedure for the simultaneous determination of cisplatin and the complex cis,cis,trans-diamminedichlorodihydroxo-platinum(IV), was development. The developed procedure was validated in terms of linearity, accuracy, precision, limits of detection (LOD), limits of quantification (LOQ) and s...

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Bibliographic Details
Main Authors: Yalexmi Ramos, Carlos Hernández, Lidia Asela Fernandez, Mayra Bataller, Eliet Veliz, Renny Small
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2011-01-01
Series:Química Nova
Subjects:
cisplatin
cis
trans-diamminedichlorodihydroxoplatinum(IV)
analytical validation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000800026&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000800026&lng=en&tlng=en

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