New evidence for the role of ceramide in the development of hepatic insulin resistance.

AIM: There are few and contradictory data on the role of excessive accumulation of intracellular sphingolipids, particularly ceramides, in the development of hepatic insulin resistance. In our study we assessed accumulated sphingolipid fractions and clarify the mechanisms of hepatic insulin resistan...

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Bibliographic Details
Main Authors: Karolina Konstantynowicz-Nowicka, Ewa Harasim, Marcin Baranowski, Adrian Chabowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4312035?pdf=render