Dendronized Silver Nanoparticles as Bacterial Membrane Permeabilizers and Their Interactions With P. aeruginosa Lipopolysaccharides, Lysozymes, and Phage-Derived Endolysins

Antimicrobial proteins, like lysozymes produced by animals or bacteriophage lysins, enable the degradation of bacterial peptidoglycan (PG) and, consequently, lead to bacterial cell lysis. However, the activity of those enzymes is not satisfactory against gram-negative bacteria because of the presenc...

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Main Authors: Karol Ciepluch, Kinga Skrzyniarz, Andrea Barrios-Gumiel, Sara Quintana, Javier Sánchez-Nieves, F. Javier de la Mata, Barbara Maciejewska, Zuzanna Drulis-Kawa, Michał Arabski
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02771/full