Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development

Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development

Human butyrylcholinesterase is a performant stoichiometric bioscavenger of organophosphorous nerve agents. It is either isolated from outdated plasma or functionally expressed in eukaryotic systems. Here, we report the production of active human butyrylcholinesterase in a prokaryotic system after op...

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Bibliographic Details
Main Authors: Xavier Brazzolotto, Alexandre Igert, Virginia Guillon, Gianluca Santoni, Florian Nachon
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
butyrylcholinesterase
prokaryotic expression
PROSS
SEC-MALS
differential scanning fluorimetry
3D structure
Online Access:https://www.mdpi.com/1420-3049/22/11/1828

Internet

https://www.mdpi.com/1420-3049/22/11/1828

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