A highly reproducible rotenone model of Parkinson's disease

The systemic rotenone model of Parkinson's disease (PD) accurately replicates many aspects of the pathology of human PD and has provided insights into the pathogenesis of PD. The major limitation of the rotenone model has been its variability, both in terms of the percentage of animals that dev...

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Bibliographic Details
Main Authors: Jason R. Cannon, Victor Tapias, Hye Mee Na, Anthony S. Honick, Robert E. Drolet, J. Timothy Greenamyre
Format: Article
Language:English
Published: Elsevier 2009-05-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109000230