Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine.

Selenoproteins are a unique group of proteins that contain selenium in the form of selenocysteine (Sec) co-translationally inserted in response to a UGA codon with the help of cis- and trans-acting factors. Mammalian selenoproteins contain single Sec residues, with the exception of selenoprotein P (...

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Bibliographic Details
Main Authors: Anton A Turanov, Robert A Everley, Sandra Hybsier, Kostja Renko, Lutz Schomburg, Steven P Gygi, Dolph L Hatfield, Vadim N Gladyshev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4599804?pdf=render