Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer.

Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer.

BACKGROUND: Aberrant DNA methylation patterns might be used as a biomarker for diagnosis and management of cancer patients. METHODS AND FINDINGS: To achieve a gene panel for developing a breast cancer blood-based test we quantitatively assessed the DNA methylation proportion of 248 CpG sites per sam...

Full description

Bibliographic Details
Main Authors: Ramin Radpour, Zeinab Barekati, Corina Kohler, Qing Lv, Nicole Bürki, Claude Diesch, Johannes Bitzer, Hong Zheng, Seraina Schmid, Xiao Yan Zhong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3025923?pdf=render

Internet

http://europepmc.org/articles/PMC3025923?pdf=render

Similar Items