Hyperandrogenism in polycystic ovarian syndrome and role of CYP gene variants: a review

Abstract Background Polycystic ovary syndrome (PCOS) is a multifactorial endocrine disorder characterized by anovulation, hyperandrogenism, and polycystic ovarian morphology. The pathophysiology of PCOS is not clear; however, disturbance in hypothalamic-pituitary-ovarian axis and abnormal steroidoge...

Full description

Bibliographic Details
Main Authors: Sairish Ashraf, Mudasar Nabi, Shayaq ul Abeer Rasool, Fouzia Rashid, Shajrul Amin
Format: Article
Language:English
Published: SpringerOpen 2019-11-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s43042-019-0031-4