Lauric Acid Is an Inhibitor of Clostridium difficile Growth in Vitro and Reduces Inflammation in a Mouse Infection Model

Lauric Acid Is an Inhibitor of Clostridium difficile Growth in Vitro and Reduces Inflammation in a Mouse Infection Model

Clostridium difficile is a Gram-positive, spore-forming anaerobic human gastrointestinal pathogen. C. difficile infection (CDI) is a major health concern worldwide, with symptoms ranging from diarrhea to pseudomembranous colitis, toxic megacolon, sepsis, and death. CDI onset and progression are most...

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Bibliographic Details
Main Authors: Hsiao-Ting Yang, Jenn-Wei Chen, Jagat Rathod, Yu-Zhen Jiang, Pei-Jane Tsai, Yuan-Pin Hung, Wen-Chien Ko, Daniel Paredes-Sabja, I-Hsiu Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Microbiology
Subjects:
Clostridium difficile
medium-chain fatty acid
lauric acid
alternative therapy
natural product
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02635/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.02635/full

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